PARKINSON &

AMINOCHROME

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Parkinson & Aminochrome

A new vision on research in idiopathic Parkinson's disease

More than 57 years have passed since L-dopa was introduced in the treatment of Parkinson's disease and today it continues to be the gold treatment despite the fact that it induces severe side effects such as dyskinesias after 4-6 years of chronic use.

Why do clinical studies of potential new drugs that were completely successful in preclinical studies fail?

Here we present an explanation for these failures and an alternative way to focus the research.

Parkinson & Aminochrome
A new vision on research in idiopathic Parkinson's disease
More than 57 years have passed since L-dopa was introduced in the treatment of Parkinson's disease and today it continues to be the gold treatment despite the fact that it induces severe side effects such as dyskinesias after 4-6 years of chronic use.

Why do clinical studies of potential new drugs that were completely successful in preclinical studies fail?

Here we present an explanation forthese failures and an alternative way to focus the research.